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However, when empagliflozin was administered with pegvisomant, a GH receptor antagonist, BHB levels were restored to baseline
This meant that the legal basis for most compounding of tirzepatide essentially disappeared
This concept is further supported by large-scale observational data (Mller et al., Diabetes Obes Metab J, 2022) showing no increased PTC risk in patients, reinforcing the safety profile
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